Reazioni avverse ai vaccini – W. Jean Doods, MDV (English version)

Viral  disease  and  recent  vaccination  with  single  or  combination  modified  live­virus  (MLV) vaccines,  especially  those  containing  distemper  virus,  adenovirus  1  or  2,  and  parvovirus  are increasingly and organ dysfunction.  Potent adjuvanted  killed  vaccines like those for rabies virus also can  trigger  immediate  and  delayed  (vaccinosis)  adverse  vaccine  reactions. Genetic predisposition gene domesticViral disease and recent vaccination with single or combination modified livevirus (MLV) vaccines, especially those containing distemper virus, adenovirus 1 or 2, and parvovirus are increasingly recognized contributors to immunemediated blood disease, bone marrow failure, and organ dysfunction. Potent adjuvanted killed vaccines like those for rabies virus also can trigger immediate and delayed (vaccinosis) adverse vaccine reactions.
Genetic  predisposition to these disorders in humans has been linked to the leucocyte antigen Drelated gene locus of the major histocompatibility complex, and is likely to have parallel associations in domestic animals.

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